Recent publications (past five years, out of 59 total):
1: Trifunovic A, Dombkowski A, Cukovic D, Mahajan P. The Potential of microRNAs
as Non-invasive Biomarkers in Acute Pediatric Asthma. J Allergy Clin Immunol.
2020 Feb 1. pii: S0091-6749(20)30121-4. doi: 10.1016/j.jaci.2020.01.032. [Epub
ahead of print] PubMed PMID: 32018032.
2: Shatara M, Xavier AC, Dombkowski A, Cukovic D, Poulik JM, Altinok D, Ge Y,
Taub JW. Monozygotic twins with neuroblastoma MS have a similar molecular
profile: a case of twin-to-twin metastasis. Br J Cancer. 2019
Nov;121(10):890-893. doi: 10.1038/s41416-019-0594-3. Epub 2019 Oct 11. PubMed
PMID: 31601961; PubMed Central PMCID: PMC6889264.
3: Shields JN, Hales EC, Ranspach LE, Luo X, Orr S, Runft D, Dombkowski A, Neely
MN, Matherly LH, Taub J, Baker TR, Thummel R. Exposure of Larval Zebrafish to the
Insecticide Propoxur Induced Developmental Delays that Correlate with Behavioral
Abnormalities and Altered Expression of hspb9 and hspb11. Toxics. 2019 Sep
21;7(4). pii: E50. doi: 10.3390/toxics7040050. PubMed PMID: 31546644; PubMed
Central PMCID: PMC6958418.
4: Dombkowski AA, Cukovic D, Bagla S, Jones M, Caruso JA, Chugani HT, Chugani DC.
TLR7 activation in epilepsy of tuberous sclerosis complex. Inflamm Res. 2019
Dec;68(12):993-998. doi: 10.1007/s00011-019-01283-3. Epub 2019 Sep 11. PubMed
PMID: 31511910; PubMed Central PMCID: PMC6823312.
5: Pan P, Dombkowski AA, Wang LS, Stoner GD. A nutrigenetic approach for
investigating the chemopreventive effects of black raspberries during the
development of preneoplastic esophagi in rats. J Berry Res. 2018;8(4):263-274.
doi: 10.3233/JBR-180346. Epub 2018 Dec 20. PubMed PMID: 30613310; PubMed Central
PMCID: PMC6319902.
6: Dyson G, Farran B, Bolton S, Craig DB, Dombkowski A, Beebe-Dimmer JL, Powell
IJ, Podgorski I, Heilbrun LK, Bock CH. The extrema of circulating miR-17 are
identified as biomarkers for aggressive prostate cancer. Am J Cancer Res. 2018
Oct 1;8(10):2088-2095. eCollection 2018. PubMed PMID: 30416858; PubMed Central
PMCID: PMC6220145.
7: Caruso JA, Carruthers NJ, Thibodeau B, Geddes TJ, Dombkowski AA, Stemmer PM.
Global Signaling Profiling in a Human Model of Tumorigenic Progression Indicates
a Role for Alternative RNA Splicing in Cellular Reprogramming. Int J Mol Sci.
2018 Sep 20;19(10). pii: E2847. doi: 10.3390/ijms19102847. PubMed PMID: 30241319;
PubMed Central PMCID: PMC6213538.
8: Bagla S, Dombkowski AA. Neuroinflammatory Nexus of Pediatric Epilepsy. J
Pediatr Epilepsy. 2018 Jun;7(2):32-39. doi: 10.1055/s-0038-1668601. Epub 2018 Sep
3. PubMed PMID: 31709125; PubMed Central PMCID: PMC6839899.
9: Farran B, Dyson G, Craig D, Dombkowski A, Beebe-Dimmer JL, Powell IJ,
Podgorski I, Heilbrun L, Bolton S, Bock CH. A study of circulating microRNAs
identifies a new potential biomarker panel to distinguish aggressive prostate
cancer. Carcinogenesis. 2018 Apr 5;39(4):556-561. doi: 10.1093/carcin/bgy025.
PubMed PMID: 29471417; PubMed Central PMCID: PMC6853653.
10: Bagla S, Cukovic D, Asano E, Sood S, Luat A, Chugani HT, Chugani DC,
Dombkowski AA. A distinct microRNA expression profile is associated with
α[(11)C]-methyl-L-tryptophan (AMT) PET uptake in epileptogenic cortical tubers
resected from patients with tuberous sclerosis complex. Neurobiol Dis. 2018
Jan;109(Pt A):76-87. doi: 10.1016/j.nbd.2017.10.004. Epub 2017 Oct 7. PubMed
PMID: 28993242; PubMed Central PMCID: PMC6070303.
11: Huang YW, Gu F, Dombkowski A, Wang LS, Stoner GD. Black raspberries
demethylate Sfrp4, a WNT pathway antagonist, in rat esophageal squamous cell
papilloma. Mol Carcinog. 2016 Nov;55(11):1867-1875. doi: 10.1002/mc.22435. Epub
2015 Nov 19. PubMed PMID: 27696538.
12: Edwards H, Rubenstein M, Dombkowski AA, Caldwell JT, Chu R, Xavier AC,
Thummel R, Neely M, Matherly LH, Ge Y, Taub JW. Gene Signature of High White
Blood Cell Count in B-Precursor Acute Lymphoblastic Leukemia. PLoS One. 2016 Aug
18;11(8):e0161539. doi: 10.1371/journal.pone.0161539. eCollection 2016. PubMed
PMID: 27536776; PubMed Central PMCID: PMC4990277.
13: Rondini EA, Duniec-Dmuchowski Z, Cukovic D, Dombkowski AA, Kocarek TA.
Differential Regulation of Gene Expression by Cholesterol Biosynthesis Inhibitors
That Reduce (Pravastatin) or Enhance (Squalestatin 1) Nonsterol Isoprenoid Levels
in Primary Cultured Mouse and Rat Hepatocytes. J Pharmacol Exp Ther. 2016
Aug;358(2):216-29. doi: 10.1124/jpet.116.233312. Epub 2016 May 25. PubMed PMID:
27225895; PubMed Central PMCID: PMC4959097.
14: Irish JC, Mills JN, Turner-Ivey B, Wilson RC, Guest ST, Rutkovsky A,
Dombkowski A, Kappler CS, Hardiman G, Ethier SP. Amplification of WHSC1L1
regulates expression and estrogen-independent activation of ERα in SUM-44 breast
cancer cells and is associated with ERα over-expression in breast cancer. Mol
Oncol. 2016 Jun;10(6):850-65. doi: 10.1016/j.molonc.2016.02.003. Epub 2016 Feb
27. PubMed PMID: 27005559; PubMed Central PMCID: PMC4920706.
15: Chen L, Martino V, Dombkowski A, Williams T, West-Mays J, Gage PJ. AP-2β Is a
Downstream Effector of PITX2 Required to Specify Endothelium and Establish
Angiogenic Privilege During Corneal Development. Invest Ophthalmol Vis Sci. 2016
Mar;57(3):1072-81. doi: 10.1167/iovs.15-18103. PubMed PMID: 26968737; PubMed
Central PMCID: PMC4790471.
16: Barrett KG, Fang H, Cukovic D, Dombkowski AA, Kocarek TA, Runge-Morris M.
Upregulation of UGT2B4 Expression by 3'-Phosphoadenosine-5'-Phosphosulfate
Synthase Knockdown: Implications for Coordinated Control of Bile Acid
Conjugation. Drug Metab Dispos. 2015 Jul;43(7):1061-70. doi:
10.1124/dmd.114.061440. Epub 2015 May 6. PubMed PMID: 25948711; PubMed Central
PMCID: PMC4468435.
17: Dombkowski AA, Batista CE, Cukovic D, Carruthers NJ, Ranganathan R, Shukla U,
Stemmer PM, Chugani HT, Chugani DC. Cortical Tubers: Windows into Dysregulation
of Epilepsy Risk and Synaptic Signaling Genes by MicroRNAs. Cereb Cortex. 2016
Mar;26(3):1059-71. doi: 10.1093/cercor/bhu276. Epub 2014 Dec 1. PubMed PMID:
25452577; PubMed Central PMCID: PMC4737604.
as Non-invasive Biomarkers in Acute Pediatric Asthma. J Allergy Clin Immunol.
2020 Feb 1. pii: S0091-6749(20)30121-4. doi: 10.1016/j.jaci.2020.01.032. [Epub
ahead of print] PubMed PMID: 32018032.
2: Shatara M, Xavier AC, Dombkowski A, Cukovic D, Poulik JM, Altinok D, Ge Y,
Taub JW. Monozygotic twins with neuroblastoma MS have a similar molecular
profile: a case of twin-to-twin metastasis. Br J Cancer. 2019
Nov;121(10):890-893. doi: 10.1038/s41416-019-0594-3. Epub 2019 Oct 11. PubMed
PMID: 31601961; PubMed Central PMCID: PMC6889264.
3: Shields JN, Hales EC, Ranspach LE, Luo X, Orr S, Runft D, Dombkowski A, Neely
MN, Matherly LH, Taub J, Baker TR, Thummel R. Exposure of Larval Zebrafish to the
Insecticide Propoxur Induced Developmental Delays that Correlate with Behavioral
Abnormalities and Altered Expression of hspb9 and hspb11. Toxics. 2019 Sep
21;7(4). pii: E50. doi: 10.3390/toxics7040050. PubMed PMID: 31546644; PubMed
Central PMCID: PMC6958418.
4: Dombkowski AA, Cukovic D, Bagla S, Jones M, Caruso JA, Chugani HT, Chugani DC.
TLR7 activation in epilepsy of tuberous sclerosis complex. Inflamm Res. 2019
Dec;68(12):993-998. doi: 10.1007/s00011-019-01283-3. Epub 2019 Sep 11. PubMed
PMID: 31511910; PubMed Central PMCID: PMC6823312.
5: Pan P, Dombkowski AA, Wang LS, Stoner GD. A nutrigenetic approach for
investigating the chemopreventive effects of black raspberries during the
development of preneoplastic esophagi in rats. J Berry Res. 2018;8(4):263-274.
doi: 10.3233/JBR-180346. Epub 2018 Dec 20. PubMed PMID: 30613310; PubMed Central
PMCID: PMC6319902.
6: Dyson G, Farran B, Bolton S, Craig DB, Dombkowski A, Beebe-Dimmer JL, Powell
IJ, Podgorski I, Heilbrun LK, Bock CH. The extrema of circulating miR-17 are
identified as biomarkers for aggressive prostate cancer. Am J Cancer Res. 2018
Oct 1;8(10):2088-2095. eCollection 2018. PubMed PMID: 30416858; PubMed Central
PMCID: PMC6220145.
7: Caruso JA, Carruthers NJ, Thibodeau B, Geddes TJ, Dombkowski AA, Stemmer PM.
Global Signaling Profiling in a Human Model of Tumorigenic Progression Indicates
a Role for Alternative RNA Splicing in Cellular Reprogramming. Int J Mol Sci.
2018 Sep 20;19(10). pii: E2847. doi: 10.3390/ijms19102847. PubMed PMID: 30241319;
PubMed Central PMCID: PMC6213538.
8: Bagla S, Dombkowski AA. Neuroinflammatory Nexus of Pediatric Epilepsy. J
Pediatr Epilepsy. 2018 Jun;7(2):32-39. doi: 10.1055/s-0038-1668601. Epub 2018 Sep
3. PubMed PMID: 31709125; PubMed Central PMCID: PMC6839899.
9: Farran B, Dyson G, Craig D, Dombkowski A, Beebe-Dimmer JL, Powell IJ,
Podgorski I, Heilbrun L, Bolton S, Bock CH. A study of circulating microRNAs
identifies a new potential biomarker panel to distinguish aggressive prostate
cancer. Carcinogenesis. 2018 Apr 5;39(4):556-561. doi: 10.1093/carcin/bgy025.
PubMed PMID: 29471417; PubMed Central PMCID: PMC6853653.
10: Bagla S, Cukovic D, Asano E, Sood S, Luat A, Chugani HT, Chugani DC,
Dombkowski AA. A distinct microRNA expression profile is associated with
α[(11)C]-methyl-L-tryptophan (AMT) PET uptake in epileptogenic cortical tubers
resected from patients with tuberous sclerosis complex. Neurobiol Dis. 2018
Jan;109(Pt A):76-87. doi: 10.1016/j.nbd.2017.10.004. Epub 2017 Oct 7. PubMed
PMID: 28993242; PubMed Central PMCID: PMC6070303.
11: Huang YW, Gu F, Dombkowski A, Wang LS, Stoner GD. Black raspberries
demethylate Sfrp4, a WNT pathway antagonist, in rat esophageal squamous cell
papilloma. Mol Carcinog. 2016 Nov;55(11):1867-1875. doi: 10.1002/mc.22435. Epub
2015 Nov 19. PubMed PMID: 27696538.
12: Edwards H, Rubenstein M, Dombkowski AA, Caldwell JT, Chu R, Xavier AC,
Thummel R, Neely M, Matherly LH, Ge Y, Taub JW. Gene Signature of High White
Blood Cell Count in B-Precursor Acute Lymphoblastic Leukemia. PLoS One. 2016 Aug
18;11(8):e0161539. doi: 10.1371/journal.pone.0161539. eCollection 2016. PubMed
PMID: 27536776; PubMed Central PMCID: PMC4990277.
13: Rondini EA, Duniec-Dmuchowski Z, Cukovic D, Dombkowski AA, Kocarek TA.
Differential Regulation of Gene Expression by Cholesterol Biosynthesis Inhibitors
That Reduce (Pravastatin) or Enhance (Squalestatin 1) Nonsterol Isoprenoid Levels
in Primary Cultured Mouse and Rat Hepatocytes. J Pharmacol Exp Ther. 2016
Aug;358(2):216-29. doi: 10.1124/jpet.116.233312. Epub 2016 May 25. PubMed PMID:
27225895; PubMed Central PMCID: PMC4959097.
14: Irish JC, Mills JN, Turner-Ivey B, Wilson RC, Guest ST, Rutkovsky A,
Dombkowski A, Kappler CS, Hardiman G, Ethier SP. Amplification of WHSC1L1
regulates expression and estrogen-independent activation of ERα in SUM-44 breast
cancer cells and is associated with ERα over-expression in breast cancer. Mol
Oncol. 2016 Jun;10(6):850-65. doi: 10.1016/j.molonc.2016.02.003. Epub 2016 Feb
27. PubMed PMID: 27005559; PubMed Central PMCID: PMC4920706.
15: Chen L, Martino V, Dombkowski A, Williams T, West-Mays J, Gage PJ. AP-2β Is a
Downstream Effector of PITX2 Required to Specify Endothelium and Establish
Angiogenic Privilege During Corneal Development. Invest Ophthalmol Vis Sci. 2016
Mar;57(3):1072-81. doi: 10.1167/iovs.15-18103. PubMed PMID: 26968737; PubMed
Central PMCID: PMC4790471.
16: Barrett KG, Fang H, Cukovic D, Dombkowski AA, Kocarek TA, Runge-Morris M.
Upregulation of UGT2B4 Expression by 3'-Phosphoadenosine-5'-Phosphosulfate
Synthase Knockdown: Implications for Coordinated Control of Bile Acid
Conjugation. Drug Metab Dispos. 2015 Jul;43(7):1061-70. doi:
10.1124/dmd.114.061440. Epub 2015 May 6. PubMed PMID: 25948711; PubMed Central
PMCID: PMC4468435.
17: Dombkowski AA, Batista CE, Cukovic D, Carruthers NJ, Ranganathan R, Shukla U,
Stemmer PM, Chugani HT, Chugani DC. Cortical Tubers: Windows into Dysregulation
of Epilepsy Risk and Synaptic Signaling Genes by MicroRNAs. Cereb Cortex. 2016
Mar;26(3):1059-71. doi: 10.1093/cercor/bhu276. Epub 2014 Dec 1. PubMed PMID:
25452577; PubMed Central PMCID: PMC4737604.
Patents
Kim, H.S., Dombkowski A.A., Novak, R., and Haab, B., Chip production, hybridization and data interpretation of antibody and protein microarrays. U.S. patent 8,765,641.
Kane, M.D., Nagel, A.C. and Dombkowski, A.A., Compositions and Systems for Identifying and Comparing Expressed Genes (mRNAs) in Eukaryotic Organisms, U.S. patent 6,955,876. |